Wintermark P, Lapointe A, Steinhorn R, Rampakakis E, Burhenne J, Meid AD, Bajraktari-Sylejmani G, Khairy M, Altit G, Adamo MT, Poccia A, Gilbert G, Saint-Martin C, Toffoli D, Vachon J, Hailu E, Colin P, Haefeli WE. Feasibility and safety of sildenafil to repair brain injury secondary to birth asphyxia (SANE-01): A randomized, double-blind, placebo-controlled phase Ib clinical trial. J Pediatr. 2023;266:113879.  doi: 10.1016/j.jpeds.2023.113879. 


Molloy EJ, El-Dib M, Soul J, Juul S, Gunn AJ, Bender M, Gonzalez F, Bearer C, Wu Y, Robertson NJ, Cotton M, Branagan A, Hurley T, Tan S, Laptook A, Austin T, Mohammad K, Rogers E, Luyt K, Wintermark P, Bonifacio SL; Newborn Brain Society Guidelines and Publications Committee. Neuroprotective therapies in the NICU in preterm infants: present and future (Neonatal Neurocritical Care Series). Pediatr Res. 2023. doi: 10.1038/s41390-023-02895-6. Epub ahead of print. 


Krzyzanski W, Wintermark P, Annaert P, Groenendaal F, Şahin S, Öncel MY, Armangil D, Koc E, Battin MR, Gunn AJ, Frymoyer A, Chock VY, Keles E, Mekahli D, van den Anker J, Smits A, Allegaert K. A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia. AAPS J. 2023;26(1):4. doi: 10.1208/s12248-023-00851-0.


Kilmartin KC, Al Balushi A, Altit G, Lapointe A, Rampakakis E, Barbosa Vargas S, Maluorni J, Wintermark P. Impact of persistent Pulmonary hypertension and oxygenation on brain injury in neonates with neonatal encephalopathy treated with therapeutic hypothermia. J Perinatol.

https://www.researchsquare.com/article/rs-3837810/v1


Elias P, Lapointe A, Wintermark P, Moore SS, Villegas Martinez D, Simoneau J, Altit G. Left Ventricular Function and Dimensions Are Altered Early in Infants Developing Brain Injury in the Setting of Neonatal Encephalopathy. J Pediatr. 2023;261:113585. doi: 10.1016/j.jpeds.2023.113585. 


Easson K, Khairy M, Rohlicek CV, Saint-Martin C, Gilbert G, Nguyen KA, Luu TM, Couture É, Nuyt AM, Wintermark P, Deoni SCL, Descoteaux M, Brossard-Racine M. A comparison of altered white matter microstructure in youth born with congenital heart disease or born preterm. Front Neurol. 2023;14:1167026. doi: 10.3389/fneur.2023.1167026. 


Brossard-Racine M, Rampakakis E, Tardif CL, Gilbert G, White A, Luu TM, Gallagher A, Pinchefsky E, Montreuil T, Simard MN, Wintermark P. Long-term consequences of neonatal encephalopathy in the hypothermia era: protocol for a follow-up cohort study at 9 years of age. BMJ Open. 2023;13(4):e073063. doi: 10.1136/bmjopen-2023-073063. 


Laval N, Paquette M, Talsmat H, Marandyuk B, Wintermark P, Pinchefsky E, Tremblay S. Exposure to maternal diabetes during pregnancy is associated with aggravated short-term neonatal and neurological outcomes following perinatal hypoxic-ischemic encephalopathy. Am J Perinatol. 2023. doi: 10.1055/a-2053-7904. Epub ahead of print. 


Pekeles H, Al Amrani F, Perez-Morgui M, Wintermark P, Shevell M. Characteristics of children with cerebral palsy in the post-therapeutic hypothermia era. J Child Neurol. 2023;38(3-4):130-136. doi: 10.1177/08830738231159162. 


Mohammad K, McIntosh S, Lee KS, Beltempo M, Afifi J, Tremblay S, Shah P, Wilson D, Bodani J, Khurshid F, Makary H, Ng E, Wintermark P; NeoBrainNetwork. Variations in care of neonates during therapeutic hypothermia: call for care practice bundle implementation. Pediatr Res. 2023;94(1):321-330. doi: 10.1038/s41390-022-02453-6. 


Patel S, Martel-Bucci A, Wintermark P, Shalish W, Claveau M, Beltempo M. Optimizing timing and frequency of head ultrasound screening for severe brain injury among preterm infants born <32 weeks' gestation. J Matern Fetal Neonatal Med. 2022;35(26):10330-10336. doi: 10.1080/14767058.2022.2128647. 


Allegaert K, Mekahli D, Wintermark P, Groenendaal F, Borloo N, Laenen A, Annaert P, Şahin S, Öncel MY, Chock VY, Armangil D, Koc E, Battin MR, Frymoyer A, Keles E, Smits A. Rescaling creatinine centiles in neonates treated with therapeutic hypothermia for neonatal encephalopathy. Neonatology. 2022;119(6):792-794. doi: 10.1159/000526738. 


Cascio A, Ferrand A, Racine E, St-Hilaire M, Sanon PN, Gorgos A, Wintermark P. Discussing brain magnetic resonance imaging results for neonates with hypoxic-ischemic encephalopathy treated with hypothermia: A challenge for clinicians and parents. eNeurologicalSci. 2022;29:100424. doi: 10.1016/j.ensci.2022.100424.


Khorram B, Kilmartin KC, Dahan M, Zhong YJ, Abdelmageed W, Wintermark P, Shah PS. Outcomes of neonates with a 10-min Apgar score of zero: A Systematic review and meta-analysis. Neonatology. 2022;119(6):669-685. doi: 10.1159/000525926. 


Keles E, Wintermark P, Groenendaal F, Borloo N, Smits A, Laenen A, Mekahli D, Annaert P, Şahin S, Öncel MY, Chock V, Armangil D, Koc E, Battin MR, Frymoyer A, Allegaert K. Serum creatinine patterns in neonates treated with therapeutic hypothermia for neonatal encephalopathy. Neonatology. 2022;42(7):930-936. doi: 10.1159/000525574.


Gurram Venkata SKR, Shah PS, Beltempo M, Yoon E, Wood S, Hicks M, Daboval T, Wong J, Wintermark P, Mohammad K; Canadian Neonatal Network Investigators. Outcomes of infants with hypoxic-ischemic encephalopathy during COVID-19 pandemic lockdown in Canada: a cohort study. Childs Nerv Syst. 2022;38(9):1727-1734. doi: 10.1007/s00381-022-05575-8. 


Xiong Y, Wintermark P. The role of sildenafil in treating brain injuries in adults and neonates. Front Cell Neurosci. 2022;16:879649. doi: 10.3389/fncel.2022.879649.


Nanyunja C, Sadoo S, Mambule I, Mathieson SR, Nyirenda M, Webb EL, Mugalu J, Robertson NJ, Nabawanuka A, Gilbert G, Bwambale J, Martinello K, Bainbridge A, Lubowa S, Srinivasan L, Ssebombo H, Morgan C, Hagmann C, Cowan FM, Le Doare K, Wintermark P, Kawooya M, Boylan GB, Nakimuli A, Tann CJ. Protocol for the birth asphyxia in African newborns (Baby BRAiN) Study: a neonatal encephalopathy feasibility cohort study. Gates Open Res. 2022;6:10 (https://doi.org/10.12688/gatesopenres.13557.1)


Beltempo M, Wintermark P, Mohammad K, Jabbour E, Afifi J, Shivananda S, Louis D, Redpath S, Lee KS, Fajardo C, Shah PS; Canadian Neonatal Network Investigators. Variations in practices and outcomes of neonates with hypoxic ischemic encephalopathy treated with therapeutic hypothermia across tertiary NICUs in Canada. J Perinatol. 2022;42(7):898-906. doi: 10.1038/s41372-022-01412-7.


Chau V, Bonifacio SL, Wintermark P; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Neonatal seizures: Challenges and the road ahead. Pediatr Neurol. 2022;128:76. doi: 10.1016/j.pediatrneurol.2021.11.014. [Editorial]


 Yazdani A, Howidi B, Shi MZ, Tugarinov N, Khoja Z, Wintermark P. Sildenafil improves hippocampal brain injuries and restores neuronal development after neonatal hypoxia-ischemia in male rat pups. Sci Rep. 2021;11(1):22046. doi: 10.1038/s41598-021-01097-6. 


Al Amrani F, Sébire G, Chen MF, Wintermark P, Saint-Martin C. Distinctive neuroimaging pattern in term newborns with neonatal placental encephalopathy: A case series. Pediatr Neurol. 2021;126:74-79. doi: 10.1016/j.pediatrneurol.2021.09.020. 


Wisnowski JL, Wintermark P, Bonifacio SL, Smyser CD, Barkovich AJ, Edwards AD, de Vries LS, Inder TE, Chau V; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Neuroimaging in the term newborn with neonatal encephalopathy. Semin Fetal Neonatal Med. 2021;26(5):101304. doi: 10.1016/j.siny.2021.101304. 


Wintermark P, Mohammad K, Bonifacio SL; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Proposing a care practice bundle for neonatal encephalopathy during therapeutic hypothermia. Semin Fetal Neonatal Med. 2021;26(5):101303. doi: 10.1016/j.siny.2021.101303.


Penn AA, Wintermark P, Chalak LF, Armstrong J, Redline R, Scher MS, Nelson KB; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Placental contribution to neonatal encephalopathy. Semin Fetal Neonatal Med. 2021;26(4):101276. doi: 10.1016/j.siny.2021.101276.


Warton FL, Molteno CD, Warton CM, Wintermark P, Lindinger NM, Dodge NC, Zöllei L, van der Kouwe AJ, Carter RC, Jacobson JL, Jacobson SW, Meintjes EM.  Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes. Alcohol Clin Exp Res. 2021;45(9):1762-1774. doi: 10.1111/acer.14672.


Chakkarapani AA, Aly H, Benders M, Cotten CM, El-Dib M, Gressens P, Hagberg H, Sabir H, Wintermark P, Robertson NJ; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Therapies for neonatal encephalopathy: Targeting the latent, secondary and tertiary phases of evolving brain injury. Semin Fetal Neonatal Med. 2021;26(5):101256. doi: 10.1016/j.siny.2021.101256. 


Wintermark P, El Dib M, Bonifacio SL; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Unanswered questions in neonates with NE. Semin Fetal Neonatal Med. 2021;26(5):101260. doi: 10.1016/j.siny.2021.101260. [Editorial].


Wintermark P, El Dib M, Bonifacio SL; on behalf of the Newborn Brain Society Guidelines and Publications Committee. Issues in the daily management of neonates with NE. Semin Fetal Neonatal Med. 2021;26(4):101255. doi: 10.1016/j.siny.2021.101255. [Editorial].


Olivieri B, Rampakakis E, Gilbert G, Fezoua A, Wintermark P. Myelination is impaired in neonates following birth asphyxia. Neuroimage: Clin. 2021;31:102678. doi: 10.1016/j.nicl.2021.102678. 


 Lam J, Tomaszewski P, Gilbert G, Moreau JT, Guiot MC, Albrecht S, Farmer JP, Atkinson J, Saint-Martin C, Wintermark P, Bernhardt B, Baillet S, Dudley RWR. The utility of arterial spin labeling (ASL) in the pre-surgical evaluation of poorly-defined focal epilepsy in children. Journal of Neurosurgery: Pediatrics 2020;27(3):243-252. doi: 10.3171/2020.7.PEDS20397.


Debay A, Patel S, Wintermark P, Claveau M, Olivier F, Beltempo M. Association of location of intubation procedure and number of tracheal intubation attempts with death or severe neurological injury among very preterm infants. Am J Perinatol. 2020;39(7):776-785. doi: 10.1055/s-0040-1718577.


Giesinger RE, Levy PT, Ruoss LW, El Dib M, Mohammad K, Wintermark P, McNamara PJ. Cardiovascular management following hypoxic ischemic encephalopathy in North America: Need for physiologic consideration. Pediatr Res. 2021;90(3):600-607. doi: 10.1038/s41390-020-01205-8.


Warton FL, Taylor PA, Warton CMR, Molteno CD, Wintermark P, Zöllei L, van der Kouwe AJ, Jacobson JL, Jacobson SW, Meintjes EM. Reduced fractional anisotropy in projection, association, and commissural fiber networks in neonates with prenatal methamphetamine exposure. Dev Neurobiol. 2020;80(11-12):381-398. doi: 10.1002/dneu.22784.


Sabsabi B, Huet C, Rampakakis E, Beltempo M, Brown R, Lodygensky GA, Piedboeuf B, Wintermark P. Asphyxiated neonates treated with hypothermia: Birth place matters. Am J Perinatol. 2020;39(3):298-306. doi: 10.1055/s-0040-1715823. 


Al Amrani F, Racine E, Shevell M, Wintermark P. Death after birth asphyxia in the cooling era. J Pediatr. 2020;226:289-293. doi: 10.1016/j.jpeds.2020.07.041. 


Xu EH, Claveau M, Yoon E, Barrington KJ, Mohammad K, Shah P, Wintermark P; on behalf of the Canadian Neonatal Network (CNN). Neonates with hypoxic-ischemic encephalopathy treated with hypothermia: Observations in a large Canadian population and determinants of death and/or brain injury. J Neonatal Perinatal Med. 2020;13(4):449-458. doi: 10.3233/NPM-190368.


Ying X, Wintermark P. Therapeutic interventions for fetal inflammatory response syndrome (FIRS). Semin Fetal Neonatal Med. 2020; 25(4):101112. doi: 10.1016/j.siny.2020.101112. [Invited Review].


Xu EH, Mandel V, Huet C, Rampakakis E, Brown RN, Wintermark P. Maternal risk factors for adverse outcome in asphyxiated newborns treated with hypothermia: Parity and labor duration matter. J Matern Fetal Neonatal Med. 2021;34(24):4123-4131. doi: 10.1080/14767058.2019.1706472. 


Goswami I, Whyte H, Wintermark P, Mohammad K, Shivananda S, Louis D, Yoon E, Shah P; on behalf of the Canadian Neonatal Network (CNN). Characteristics and short-term outcomes of neonates with mild hypoxic-ischemic encephalopathy treated with hypothermia. J Perinatol. 2020;40(2):275-283. doi: 10.1038/s41372-019-0551-2.


Easson K, Rohlicek CV, Houde JC, Gilbert G, Saint-Martin C, Fontes K, Majnemer A, Marelli A, Wintermark P, Descoteaux M, Brossard-Racine M. Quantification of apparent axon density and orientation dispersion in the white matter of youth born with congenital heart disease. NeuroImage. 2020;205:116255. doi: 10.1016/j.neuroimage.2019.116255.


Selewski DT, Gist KM, Nathan AT, Goldstein SL, Boohaker LJ, Akcan-Arikan A, Bonachea EM, Hanna M, Joseph CX, Mahan JD, Mammen C, Nada A, Reidy K, Staples A, Wintermark P, Griffin R, Askenazi DJ, and Guillet R; on behalf of the Neonatal Kidney Collaborative. The impact of fluid balance on outcomes in premature neonates: A report from the AWAKEN study group. Pediatr Res. 2019;85(1):79-85. doi: 10.1038/s41390-019-0579-1.


Zhong YJ, Claveau M, Yoon E, Aziz K, Singhal N, Shah PS, Wintermark P; on behalf of the Canadian Neonatal Network (CNN) Investigators. Neonates with a 10-minute Apgar score of zero: Outcomes by gestational age. Resuscitation. 2019;143:77-84. doi: 10.1016/j.resuscitation.2019.07.036.


Beltempo M, Wintermark P, Lemyre B, Shalish W, Martel-Bucci A, Narvey M, Ng EH, Guillot M, Shah PS; Canadian Neonatal Network Investigators. Predictors of severe neurologic injury on ultrasound scan of the head and risk factor-based screening for infants born preterm. J Pediatr. 2019;214:27-33.e3. doi: 10.1016/j.jpeds.2019.06.065.


La Haye-Caty N, Barbosa Vargas B, Maluorni J, Rampakakis E, Zappitelli M, Wintermark P. Impact of restricting fluid and sodium intake in term asphyxiated newborns treated with hypothermia. J Matern Fetal Neonatal Med. 2020; 33(20):3521-3528. doi: 10.1080/14767058.2019.1578747.


Selewski DT, Akcan-Arika A, Bonachea EM, Gist KM, Goldstein S, Hanna M, Joseph C, Mahan J, Nada A, Nathan AT, Reidy K, Staples A, Wintermark P, Boohaker LJ, Griffin R, Askenazi DJ, Guillet R; on behalf of the Neonatal Kidney Collaborative. The impact of fluid balance on outcomes in critically ill near-term/term neonates: A report from the AWAKEN study group. Pediatr Res. 2018; 85(1):79-85. doi: 10.1007/s00467-018-4106-0.


Wang H, Beltempo M, Rampakakis E, Sanon PN, Barbosa Vargas B, Maluorni J, Saint-Martin C, Wintermark P. Illness severity predicts death and brain injury in asphyxiated newborns treated with hypothermia. Am J Perinatol. 2018; 35(10):951-958. doi: 10.1055/s-0038-1632368.


 Al Amrani F, Marcovitz J, Sanon PN, Khairy M, Saint-Martin C, Shevell M, Wintermark P. Prediction of outcome in asphyxiated newborns treated with hypothermia: Is a MRI scoring system described before the cooling era still useful? Eur J Paediatr Neurol. 2018;22(3):387-395. doi: 10.1016/j.ejpn.2018.01.017.


Lopez Laporte M, Wang H, Sanon PN, Barbosa Vargas B, Maluorni J, Rampakakis E, Wintermark P. Effect of the ventilation and the partial pressure of carbon dioxide during the first days of life on the development of brain injury in asphyxiated newborns treated with hypothermia. J Matern Fetal Neonatal Med. 2017;32(8):1312-1320. doi: 10.1080/14767058.2017.1404980.


Warton FL, Meintjes EM, Warton CMR, Molteno CD, Lindinger NM, Colin Carter R, Zöllei L, Wintermark P, Jacobson JL, van der Kouwe A, Jacobson SW. Prenatal methamphetamine exposure is associated with reduced subcortical volumes in neonates. Neurotoxicol Teratol. 2017;65:51-59. doi: 10.1016/j.ntt.2017.10.005. 


Warton FL, Taylor PA, Warton CMR, Molteno CD, Wintermark P, Lindinger NM, Zöllei L, van der Kouwe A, Jacobson JL, Jacobson SW, Meintjes EM. Prenatal methamphetamine exposure is associated with corticostriatal white matter changes in neonates. Metab Brain Dis. 2018;33(2):507-522. doi: 10.1007/s11011-017-0135-9. 


Owji ZP, Gilbert G, Saint-Martin C, Wintermark P. Brain temperature is increased during the first days of life in asphyxiated newborns developing brain injury despite hypothermia treatment. AJNR Am J Neuroradiol. 2017;38(11):2180-2186. doi: 10.3174/ajnr.A5350. 


Al Balushi A, Barbosa Vargas B, Maluorni J, Sanon PN, Rampakakis E, Saint-Martin C, Wintermark P. Hypotension in term asphyxiated newborns treated with hypothermia and its impact on the neonatal brain. Am J Perinatol. 2017;35(1):31-38. doi: 10.1055/s-0037-1604392. 


Al Amrani F, Kwan S, Gilbert G, Saint-Martin C, Shevell M, Wintermark P. Early imaging and adverse neurodevelopmental outcome in asphyxiated newborns treated with hypothermia. Pediatr Neurol. 2017;73:20-27. doi: 10.1016/j.pediatrneurol.2017.04.025. 


Garfinkle J, Wintermark P, Shevell MI, Oskoui M. Cerebral palsy following suspected asphyxia: Are moderate-late preterm similar to term? J Perinatol. 2017 [Epub ahead of print]. 

http://www.nature.com/jp/journal/vaop/ncurrent/full/jp201723a.html


Jacobson SW, Jacobson JL, Molteno CD, Warton CMR, Wintermark P, Taylor P, Warton F, Lindinger NM, Dodge NC, Grant E, Warfield SK, Zollei L, van der Kouwe A, Meintjes EM. Heavy prenatal alcohol exposure is related to smaller corpus callosum in newborn MRI scans. Alcohol Clin Exp Res. 2017;41(5):965-975. 

http://onlinelibrary.wiley.com/doi/10.1111/acer.13363/abstract;jsessionid=6CDB33E450D04F6F834C0B6A80317D9D.f03t01


Racine E, Bell E, Farlow B, Miller S, Payot P, Rasmussen LA, Shevell M, Thomson D, Wintermark P. “ouR-HOPE” approach for ethics and communication about neonatal neurological injury. Dev Med Child Neurol. 2017;59(2):125-135.

http://onlinelibrary.wiley.com/doi/10.1111/dmcn.13343/abstract


Yazdani A, Khoja Z, Johnstone A, Dale L, Rampakakis E, Wintermark P. Sildenafil improves brain injury recovery following term neonatal hypoxia-ischemia in male rat pups. Dev Neurosci. 2016;38(4):251-263. 

https://www.karger.com/Article/Abstract/448327


Jung S, Johnstone A, Khoja Z, Rampakakis E, Lachapelle P, Wintermark P. Sildenafil improves functional and structural outcome of retinal injury following term neonatal hypoxia-ischemia. Invest Ophthalmol Vis Sci. 2016;57(10):4306-4314.

http://iovs.arvojournals.org/article.aspx?articleid=2546645


Gagnon MH, Wintermark P. Effect of persistent pulmonary hypertension on brain oxygenation in asphyxiated term newborns treated with hypothermia. J Matern Fetal Neonatal Med. 2016;29(13):2049-2055. 

http://www.tandfonline.com/doi/abs/10.3109/14767058.2015.1077221?journalCode=ijmf20


Lechpammer M, Tran YP, Wintermark P, Martinez-Cerdeno V, Ahmed W, Berman RF, Jensen FE, Nudler E, Zagzag D. Upregulation of cystathione β-synthase and p70S6K/S6 in neonatal hypoxic-ischemic brain injury. Brain Pathol. 2016 [Epub ahead of print]. 

http://onlinelibrary.wiley.com/doi/10.1111/bpa.12421/abstract


Courteau C, Samman K, Ali N, Riley P, Wintermark P. Macrosomia and hemodynamic instability may represent risk factors for subcutaneous fat necrosis in asphyxiated newborns treated with hypothermia. Acta Paediatr. 2016;105(9):e396-e405. 

http://onlinelibrary.wiley.com/doi/10.1111/apa.13463/abstract


Poon AWH, Ma EXH, Vadivel A, Jung S, Khoja Z, Stephens L, Thebaud B, Wintermark P. Impact of bronchopulmonary dysplasia on brain and retina. Biol Open. 2016;5(4):475-483. 

http://bio.biologists.org/content/5/4/475.long


Al Balushi A, Guibault MP, Wintermark P. Secondary increase of lactate levels in asphyxiated newborns during hypothermia treatment: A reflect of suboptimal hemodynamics (A case series). AJP Rep. 2016;6(1):e48-e58. 

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0035-1565921


Bolbocean C, Wintermark P, Shevell M, Oskoui M. Perinatal regionalization and implications for long-term health outcomes in cerebral palsy. Can J Neurol Sci. 2016;43(2):248-253.

https://www.cambridge.org/core/journals/canadian-journal-of-neurological-sciences/article/perinatal-regionalization-and-implications-for-longterm-health-outcomes-in-cerebral-palsy/D97E934146A56D10242D2503234D1481


Benini R, Roth R, Khoja Z, Avoli M, Wintermark P. Does angiogenesis play a role in the establishment of mesial temporal lobe epilepsy? Int J Dev Neurosci 2016;49:31-36. 

http://www.sciencedirect.com/science/article/pii/S0736574815301532


Garfinkle J, Wintermark P, Shevell MI, Oskoui M. Cerebral palsy following neonatal encephalopathy: A population-based study of outcomes. Dev Med Child Neurol. 2016;58(2):189-194.

http://onlinelibrary.wiley.com/doi/10.1111/dmcn.12953/abstract


Gagne-Loranger M, Sheppard M, Ali N, Saint-Martin C, Wintermark P. Newborns referred for cooling: Association between initial degree of encephalopathy and severity of brain injury (What about the newborns with a mild encephalopathy on admission?). Am J Perinatol. 2016;33(2):195-202.

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0035-1563712


Wintermark P, Lechpammer M, Kosaras B, Jensen FE, Warfield SK. Brain perfusion is increased at term in the white matter of very preterm newborns and newborns with congenital heart disease: May this reflect activated angiogenesis? Neuropediatrics. 2015;46(5):344-351. 

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0035-1563533


Al Yazidi G, Boudes E, Tan X, Saint-Martin C, Shevell M, Wintermark P. Intraventricular hemorrhage in the asphyxiated newborns treated with hypothermia: A look into incidence, timing and risk factors. BMC Pediatrics. 2015: 15(1):106.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551518/pdf/12887_2015_Article_415.pdf


Jung S, Polosa A, Lachapelle P, Wintermark P. Visual impairments following term neonatal encephalopathy: Do retinal impairments also play a role? (Study in a rat model of term neonatal hypoxia-ischemia. Invest Ophthalmol Vis Sci. 2015;56(9):5182-5193.

http://iovs.arvojournals.org/article.aspx?articleid=2424443


Lechpammer M, Wintermark P, Merry KM, Jackson MC, Jantzie LL, Jensen FE. Dysregulation of FMRP/mTOR signaling cascade in hypoxic-ischemic injury of premature human brain. J Child Neurol. 2015 [Epub ahead of print].

http://jcn.sagepub.com/content/early/2015/07/29/0883073815596617.long


Kwan S, Boudes E, Benseler A, Gilbert G, Saint-Martin C, Shevell M, Wintermark P. Evolution of apparent diffusion coefficient and fractional anisotropy in the cerebrum of asphyxiated newborns treated with hypothermia over the first month of life. Neural Plast. 2015;653727.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503577/pdf/NP2015-653727.pdf


Kwan S, Boudes E, Gilbert G, Saint-Martin C, Albrecht S, Shevell M, Wintermark P. Injury to the cerebellum in term asphyxiated newborns treated with hypothermia. AJNR Am J Neuroradiol. 2015;36(8):1542-1549.

http://www.ajnr.org/content/36/8/1542.long


Shaikh H, Boudes E, Khoja Z, Shevell M, Wintermark P. Angiogenesis dysregulation in term asphyxiated newborns treated with hypothermia. PLoS One. 2015;10(5):e0128028. 

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440713/pdf/pone.0128028.pdf


Garfinkle J, Wintermark P, Shevell MI, Oskoui M. Cerebral palsy following neonatal encephalopathy: How much is preventable? J Pediatr. 2015;167(1):58-63. 

http://www.jpeds.com/article/S0022-3476%2815%2900155-9/abstract


Garfinkle J, Sant’Anna GM, Rosenblatt B, Majnemer A, Wintermark P, Shevell MI. Somatosensory evoked potentials in neonates with hypoxic-ischemic encephalopathy treated with hypothermia. Eur J Paediatr Neurol. 2015;19(4):423-428. z 

http://www.ejpn-journal.com/article/S1090-3798%2815%2900045-8/abstract


Wintermark P. Injury and repair in perinatal brain injury: Insights from non-invasive MR perfusion imaging. Semin Perinatol. 2015;39(2):124-129. [Invited Review]. 

http://www.seminperinat.com/article/S0146-0005%2815%2900006-3/abstract


Lachapelle J, Chen MF, Oskoui M, Boudes E, Ali N, Brown R, Wintermark P. Placental pathology in asphyxiated newborns treated with therapeutic hypothermia. J Neonatal Perinatal Med. 2015 [Epub ahead of print].

http://content.iospress.com/articles/journal-of-neonatal-perinatal-medicine/npm814068?resultNumber=0&totalResults=16&start=0&q=wintermark+&resultsPageSize=10&rows=10


Shaikh H, Lechpammer M, Jensen FE, Warfield SK, Hansen AH, Kosaras B, Shevell M, Wintermark P. Increased brain perfusion persists over the first month of life in term asphyxiated newborns treated with hypothermia: Does it reflect activated angiogenesis? Transl Stroke Res. 2015 [Epub ahead of print]. 

http://link.springer.com/article/10.1007%2Fs12975-015-0387-9


Boudes E, Tan X, Saint-Martin C, Shevell M, Wintermark P. Magnetic resonance imaging obtained during versus after hypothermia in asphyxiated Newborns. Arch Dis Child Fetal Neonatal Ed. 2015 [Epub ahead of print]. 

http://fn.bmj.com/content/100/3/F238.long


Peng S, Boudes E, Tan X, Saint-Martin C, Shevell M, Wintermark P. Does near-Infrared spectroscopy identify asphyxiated newborns at risk of developing brain injury during hypothermia treatment? Am J Perinatol. 2015 [Epub ahead of print

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0034-1396692


Boudes E, Gilbert G, Leppert IR, Tan X, Pike GB, Saint-Martin C, Wintermark P. Measurement of brain perfusion in newborns: pulsed arterial spin labeling (PASL) versus pseudo-continuous arterial spin labeling (pCASL). Neuroimage Clin. 2014;6:126-133.

http://ac.els-cdn.com/S2213158214001193/1-s2.0-S2213158214001193-main.pdf?_tid=d54de5ca-458d-11e4-a335-00000aacb362&acdnat=1411743800_6568224cfdbaff24941f89e81828dfbe


Taylor PA, Meintjes EM, van der Kouwe A, Molteno CD, Chen G, Wintermark P, Alhamud A, Jacobson JL, Jacobson SW. A DTI-based tractography study of effects on brain structure associated with prenatal alcohol exposure in newborns. Hum Brain Mapp. 2015;36(1):170-186.

http://onlinelibrary.wiley.com/doi/10.1002/hbm.22620/abstract


Lord A, Shapiro AJ, Saint-Martin C, Claveau M, Melancon S, Wintermark P. Filamin A mutation may be associated with diffuse lung disease mimicking bronchopulmonary dysplasia in premature newborn. Respir Care. 2014;59(11):e171-7.

http://rc.rcjournal.com/content/early/2014/07/22/respcare.02847.short


Al Yazidi G, Srour M, Wintermark P. Risk factors for intraventricular hemorrhage in term asphyxiated newborns treated with hypothermia. Pediatr Neurol. 2014;50(6):630-5.

http://www.sciencedirect.com/science/article/pii/S0887899414000897


Shevell A, Wintermark P, Benini R, Shevell M, Oskoui M. Chorioamnionitis and cerebral palsy: Lessons from a patient registry. Eur J Paediatr Neurol. 2014;18(3):301-7.

http://www.sciencedirect.com/science/article/pii/S1090379813002109


Wintermark P, Lechpammer M, Warfield SK, Kosaras B, Takeoka M, Poduri A, Madsen JR, Bergin AM, Whalen S, Jensen FE. Perfusion imaging of focal cortical dysplasia using arterial spin labeling: correlation with histopathological vascular density. J Child Neurol. 2013;28(11):1474-1482.

http://jcn.sagepub.com/content/28/11/1474.abstract


Wintermark P, Hansen A, Warfield SK, Dukhovny D, Soul J. Near-infrared spectroscopy versus magnetic resonance imaging to study brain perfusion in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. NeuroImage. 2014;85 Pt 1:287-293.

http://www.sciencedirect.com/science/article/pii/S1053811913004199


Garfinkle J, Sant’Anna GM, Wintermark P, Ali N, Morneault L, Koclas L, Shevell M. Cooling in the real world: Therapeutic hypothermia in hypoxic-ischemic encephalopathy. Eur J Paediatr Neurol. 2013;17(5):492-497.

http://www.sciencedirect.com/science/article/pii/S1090379813000494


Wintermark P. Brain cooling for asphyxiated newborns: The impact on respiratory mechanics, oxygenation and ventilation. Canadian Journal of Respiratory Therapy. 2012: 48(1):13-16.

http://www.csrt.com/en/publications/files/CJRT/Spring_2012/Original_article2.asp


McMahon E, Wintermark P, Lahav A. Auditory brain development in premature infants: the importance of early experience. Ann N Y Acad of Sci. 2012; 1252(1):17-24.

http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2012.06445.x/abstract;jsessionid=F808D8EFA9AEF7C86727DDCB0A9FEDDC.d03t03


Wintermark P. The role of brain MR scanning in the newborn. Paediatrics and Child Health. 2012;22(4):155-159.

http://www.sciencedirect.com/science/article/pii/S1751722211001995


Wintermark P, Warfield SK. New insights in perinatal stroke by assessing brain perfusion. Transl Stroke Res. 2012;3(2):255-262.

http://www.springerlink.com/content/111220005345755p/


Wintermark P. Current controversies in newer therapies to treat birth asphyxia. Int J Pediatr. 2011;2011:848413.

http://www.hindawi.com/journals/ijped/2011/848413/


Wintermark P, Hansen A, Gregas MC, Soul J, Labrecque M, Robertson RL, Warfield SK. Brain perfusion in asphyxiated newborns treated with therapeutic hypothermia. AJNR Am J Neuroradiol. 2011; 32(11):2023-2029

http://www.ajnr.org/content/32/11/2023.long


Hagmann CF, Halbherr M, Koller B, Wintermark P, Huisman T, Bucher HU, and The Swiss Neonatal Network. Interobserver variability in assessment of cranial ultrasound in very preterm infants. J Neuroradiol. 2011; 38(5):291-297. 

http://www.em-consulte.com/article/675544/alertePM


Earley Lindamood K, Fleck P, Narla A, Vergilio JA, Degar BA, Baldwin M, Wintermark P. Neonatal enteroviral sepsis/meningoencephalitis and hemophagocytic lymphohistiocytosis: diagnostics challenges. Am J Perinatol. 2011;28(5):337-346.

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0030-1268710


Wintermark P, Boyd T, Gregas MC, Labrecque M, Hansen A. Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia. Am J Obstet Gynecol 2010;203(6):579.e1-9.

http://www.ajog.org/article/S0002-9378%2810%2901027-6/abstract


Wintermark P, Labrecque M, Warfield SK, DeHart S, Hansen A. Can induced hypothermia be assured during brain MRI in neonates with hypoxic-ischemic encephalopathy?Pediatr Radiol 2010; 40(12):1950-1954. 

http://www.springerlink.com/content/m1574rv9x0601786/


Wintermark P, Hansen A, Soul J, Labrecque M, Robertson RL, Warfield SK. Early versus late MRI in asphyxiated newborns treated with hypothermia.Arch Dis Child Fetal Neonatal Ed 2011;96(1):F36-44.

http://fn.bmj.com/content/96/1/F36.abstract


Wintermark P, Boyd T, Parast MM, Van Marter LJ, Warfield SK, Robertson RL, Ringer SA. Fetal placental thrombosis and neonatal implications. Am J Perinatol 2010;27(3):251-256.

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1239486


Wintermark P, Roulet-Perez E, Maeder-Ingvar M, Moessinger AC, Gudinchet F, Meuli R. Perfusion abnormalities in hemimegalencephaly. Neuropediatrics 2009;40(2):92-96.

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1237721


Laswad T, Wintermark P, Alamo L, Moessinger A, Meuli R, Gudinchet F. Method for performing cerebral perfusion-weighted MRI in neonates. Pediatr Radiol 2009;39(3):260-264.

http://www.springerlink.com/content/c9882542710185u6/


Wintermark P, Moessinger AC, Gudinchet F, Meuli R. Perfusion-weighted magnetic resonance imaging patterns of hypoxic-ischemic encephalopathy in term neonates. J Magn Reson Imaging 2008;28(4):1019-1025. 

http://onlinelibrary.wiley.com/doi/10.1002/jmri.21525/abstract;jsessionid=7B43FC9E19B97908FB043462C23EFCB3.d02t03


Wintermark P, Moessinger AC, Gudinchet F, Meuli R. Temporal evolution of perfusion-weighted imaging in neonatal hypoxic-ischemic encephalopathy. J Magn Reson Imaging 2008;27(6):1229-1234. 

http://onlinelibrary.wiley.com/doi/10.1002/jmri.21379/abstract


Wintermark P, Meagher Villemure K, Villemure JG, Maeder-Ingvar M, Maeder P, Ghariani S, Roulet-Perez E. Progressive unilateral hemispheric atrophy in an infant with neurofibromatosis. Neuropediatrics 2007;38(2):100-104. 

https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-985139


Wintermark P, Tolsa JF, Van Melle G, Forcada-Guex M, Moessinger AC. Long-term outcome of preterm infants treated with nasal continuous positive airway pressure. Eur J Pediatr 2007; 166(5): 473-483.

http://www.springerlink.com/content/69253n7357833274/